The structure, catalytic mechanism and regulation of adenylyl cyclase

John J.G. Tesmer, Stephen R. Sprang

Research output: Contribution to journalArticlepeer-review

Abstract

The recent structure determinations of the mammalian effector enzyme adenylyl cyclase reveal the structure of its catalytic core, provide new insights into its catalytic mechanism and suggest how diverse signaling molecules regulate its activity.

Original languageEnglish
Pages (from-to)713-719
Number of pages7
JournalCurrent Opinion in Structural Biology
Volume8
Issue number6
DOIs
StatePublished - Dec 1998

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