The use of phosphonitrilic dichloride cyclic trimer in oligopeptide synthesis. Synthesis of isoxazolyl-prodrugs of netropsin and distamycin

Erik J. Verner, Bradford J. Oliver, Ludwig Schlicksupp, Nicholas R. Natale

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Phosphonitrilic dichloride cyclic trimer has been found to be an effective activating agent for the synthesis of oligopeptides containing N-terminal isoxazole-4-carboxamide groups.

Original languageEnglish
Pages (from-to)327-339
Number of pages13
JournalHeterocycles
Volume31
Issue number2
DOIs
StatePublished - Feb 1 1990

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