@article{03a1660e351e49a58f6d413dfeffdce8,
title = "A novel 5-HT receptor ligand and related cytotoxic compounds from an acid mine waste extremophile",
abstract = "Berkeley Pit Lake in Butte, Montana, is an acid mine waste reservoir rich in toxic metals. A Pithomyces sp. isolated from the Pit Lake yielded three tyrosine derivatives (1-3), one of which acts as a 5-HT(2a) receptor ligand. This type of activity has been associated with migraine preventative and antihypertensive drugs. The isolation and characterization of compounds 1-3 and three sesquiterpenes (5-7) that have been isolated previously from higher plants are reported here.",
author = "Stierle, \{Andrea A.\} and Stierle, \{Donald B.\} and Eric Goldstein and Keith Parker and Tim Bugni and Chad Baarson and Julie Gress and Danielle Blake",
year = "2003",
month = aug,
day = "1",
doi = "10.1021/np030044w",
language = "English",
volume = "66",
pages = "1097--1100",
journal = "Journal of Natural Products",
issn = "0163-3864",
publisher = "American Chemical Society",
number = "8",
}